Three key indicators for spontaneous pregnancy include the woman’s ability to ovulate, the functionality of at least one tube, and seminal fluid sufficient for the natural fertilization of an egg.
Based on a couple’s diagnosis and its cause of infertility, IUI Treatment Lahore must begin gradually – starting with simple hormonal stimulation and monitoring for targeted intercourse to insemination intrauterine to in vitro fertilization treatments.
As far as intrauterine insemination techniques are concerned, hormonal stimulation with tablets or subcutaneous injections of gonadotropins should first be undertaken in order to stimulate 2-3 follicles into maturation and increase chances that at least one contains fertilized eggs as well as improve endometrial quality which is essential for embryo implantation.
Ultrasound monitoring and blood samples to measure LH and progesterone hormone levels help determine the most suitable time and place to administer HCG to induce ovulation; after approximately 34-40 hours intrauterine insemination can take place.
Seminal fluid must be prepared using a process known as “capacitation”, which involves selecting only viable spermatozoa to keep in a culture medium and aspirating them using a syringe connected to a thin sterile plastic catheter.
This outpatient procedure is quick, painless, and straightforward: the patient lies down in a gynecological position while wearing a speculum to highlight the neck of their uterus, then inserts a catheter up through their cervical canal to reach their uterine cavity where semen is then injected directly into their fallopian tubes.
After insemination, it is preferable for the woman to lie supine for several minutes in order to prevent immediate leakage of seminal fluid and then resume her daily activities.
For optimal insemination results, couples should engage in unprotected sexual relations for several days after insemination.
This will increase the odds of successful fertilization.
Insemination offers numerous advantages over targeted intercourse, including selecting and placing only high-quality sperm into the vaginal environment at once, including its protective acid pH that allows some sperm to survive for several minutes; eliminating hostility of cervical mucus; and cutting in half the distance traveled by spermatozoa until reaching their oocyte at the final part of the tube.
Intrauterine Insemination for female causes has multiple advantages; among these are:
Previous attempts have failed
Couples who have made at least three unsuccessful attempts to stimulate ovulation for targeted intercourse may opt for insemination because its greater chances of success justify making this switch.
Ovulation or Luteal Phase Disorders
Hormonal stimulation to induce follicular growth and subsequent ovulation, intrauterine insemination, and post-ovulatory progesterone supplementation have all proven successful methods for increasing the chances of pregnancy within four inseminations.
Mild endometriosis impedes egg quality and implanting ability due to inflammation-causing substances in the body, making implantation difficult and increasing success rates of IVF attempts. A slight hormonal stimulation, with the preparation of sperm for injection into uterine cavities, increases success rates further.
Cervical infections can alter the quality or quantity of mucus that protects spermatozoa from vaginal acidity by either blocking their entry into the uterine cavity or restricting their passage through it.
Antisperm antibodies present in cervical mucus or seminal plasma can immobilize and prevent sperm from reaching the uterus. Sperm capacitation and intrauterine insemination allow sperm to thin out and pass mucus more freely into the uterus, increasing the chances of conception.
Infections such as HIV or HCV can be avoided by washing the infected sperm before giving it to women for reproduction or by avoiding sexual contact between unprotected partners who carry these infections.
Intrauterine Insemination for female causes has some specific drawbacks that should be taken into consideration, including:
Age of the Woman Over 40
Studies demonstrate a gradual decrease in success rates over time with fertility treatments like IUI becoming less successful after 40. Alternatively, tubal sterility should no longer be considered a first-choice solution. Anschliessend,
In cases of tubal obstruction or damage preventing sperm from meeting an oocyte, in vitro fertilization therapy may be required to help facilitate conception.
Severe endometriosis leads to diffuse adhesion syndrome with irreparable tubal damage. Surgery or in vitro fertilization treatment will likely be necessary, and endometriosis removal surgery and IVF must be pursued immediately as necessary.
Failed IUI attempts
The probability of IUI Treatment Cost in Pakistan success per cycle averages 10% with cumulative rates estimated to reach approximately 25% within 6 attempts. Based on historical records, 85% of successful IUI cycles take place within four attempts before moving forward with IVF treatment becomes justifiable.